Author/Editor		Meden-Vrtovec, H
Title		Pure FSH (Metrodin) for ovarian stimulation in the IVF-ET programme
Type		članek
Source		Clin Exp Obstet Gynecol
Vol. and No.		Letnik 22, št. 1
Publication year		1995
Volume		str. 9-13
Language		eng
Abstract		Purpose: a comparative analysis of the clinical effectiveness of pure FSH (Metrodin) and convetional gonadotropin (Pergonal) for ovarian stimulation was performed. Methods: each group consisted of 30 selected patients with tubal infertility, practically identical by average age, duration of infertility, age at menarche, weight and height and husband's semen analysis. The average number of vials of drug used for stimulation, number of oocytes retrieved and embryos transferred was the same for both groups of patients. The failure of oocyte retrieval and fertilization was higher in the Pergonal (16.8 percent) than in the Metrodin group (6.8 percent). Results: in both groups there were 8 pregnancies - 4 in the Pergonal and 4 in Metrodin group. All pregnancies in the pure FSH group resulted in the delivery of a healthy baby, while in the Pergonal group there were two deliveries and two spontaneous abortions. Author's conclusions: evaluating the data we can conclude that pure FSH stimulation provides respectively lower failure and spontaneous abortion rates than Pergonal stimulation, leading to a higher take home baby rate.
Descriptors		OVULATION INDUCTION INFERTILITY, FEMALE FSH MENOTROPINS FERTILIZATION IN VITRO