Author/Editor		Gleber-Netto, Frederico O.; Braakhuis, Boudewijn J. M.; Triantafyllou, Asterios; Takes, Robert P.; Kelner, Natalie; Rodrigo, Juan P.; Strojan, Primož; Vander Poorten, Vincent; Rapidis, Alexander D.; Rinaldo, Alessandra; Brakenhoff, Ruud H.; Ferlito, Alfio; Kowalski, Luiz P.
Title		Molecular events in relapsed oral squamous cell carcinoma
Type		članek
Vol. and No.		Letnik 51, št. 8
Publication year		2015
Volume		str. 738-744
ISSN		1368-8375 - Oral oncology
Language		eng
Abstract		Relapses have a great impact on both the morbidity and mortality rates of oral squamous cell carcinoma (OSCC) patients. Current classification criteria are imprecise and need improvements. Recent advances in understanding of OSCC relapses on a molecular level provide new possibilities to better classify true recurrences and second primary tumors. This review discusses the limitations of the current OSCC relapse classification method and presents possible alternatives to improve this classification based on molecular techniques. Moreover, these molecular techniques add to the further understanding of these lesions and may provide tools for clinical management.
Keywords		rak grla molekuladna diagnoze ploščatocelični rak oral cancer molecular diagnosis squamous cell carcinoma