Author/Editor		Barišić, N; Lovrek, V
Title		Kritična analiza spremljanja uporabe zdravil v pediatrični ustanovi
Translated title		Critical analysis of drug use surveillance in a pediatric hospital
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 64, št. 6
Publication year		1995
Volume		str. 351-6
Language		slo
Abstract		Background. Drug use in Pediatric University Hospital was analyzed during ten-year period. Methods. Retrospective analysis of drug utilization data and patient records by programmed computerized elaboration was conducted. The analysis was performed by means of defined daily doses/1000 bed days (ODO/1000 bd). Results. Results revealed the broad spectrum penicillins were mostly administered followed by cephalosporins and corticosteroids mainly in neonatal and infant age groups. A tendency to decreased antibiotic use was observed after restriction policy was introduced. A 5 percent randomized sample of children inpatients treated for respiratory and urinary infections revealed that one third to one half of antibiotics are inappropriately prescribed. Conclusions. ODO as a surveillance method showed to be significant for simple drug utilization insight, and for continuous assessment of treatment quality and quantity in pediatric hospitals.
Summary		Izhodišča. Prispevek analizira porabo zdravil v določeni pediatrični univerzitetni bolnišnici v obdobju 10 let. Metode. Uporabljena je bila retrospektivna analiza podatkov iz računalniško obdelanih obračunskih in matičnih listov po farmakodinamskih skupinah. Podatke smo vzeli tudi iz medicinske dokumentacije o otrocih, ki so se zdravili zaradi respiratornih in urinarnih okužb. Analiza je izpeljana s pomočjo opredeljenih dnevnih odmerkov na 1000 bolnišnično oskrbljenih dni (ODO/1000 bod). Rezultati. Rezultati kažejo, da se največ uporabljajo polisintetični penicilini, zatem cefalosporini in kortikosteroisi, najpogosteje pri novorojenčkih in dojenčkih. Težnje k zmajšani uporabi antibiotikov smo opazili po uvajanju restriktivnih ukrepov oziroma antibiotikov rezerve. Usmerjena analiza 5 odst. vzorca hospitaliziranih otrok z respiratornimi oziroma urinarnimi okužbami je pokazala, da je bilo skoraj 1/3 do 1/2 antibiotikov neutemeljeno predpisanih. Zaključki. Predložene metode ODO lahko dajo dober splošni vpogled v porabo zdravil, koristna pa je tudi kot zanesljiv način pri stalnem spremljanju količine in kakovosti zdravljenja v otroških bolnišničnih ustanovah.