Author/Editor		Hojs, R
Title		Vranica pri bolnikih z analgetično nefropatijo, zdravljenih s kronično hemodializo
Translated title		Spleen in patients with analgesic nephropathy treated with maintenance haemodialysis
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 64, št. 7-8
Publication year		1995
Volume		str. 405-7
Language		slo
Abstract		Background. Analgesic nephropathy is a form of exogenous tubulointerstitial kidney disease with a progressive clinical course and frequently with a subsequent development of papillary necrosis. Splenomegaly was reported to be a part of analgesic syndrome. The aim of our study was to establish the size of the spleen in patients with analgesic nephropathy treated with maintenance haemodialysis and to compare it with the spleen size of control group patients. Methods. With real time sonography we determined the spleen size in cm2 in patients with analgesic nephropathy treated with hemodialysis. The results were compared with those in control group patients (equal number of patients matched for age and sex, randomly selected from the group of patients treated with maintenance hemodialysis without known analgesic abuse). Results. We did not find any statistically significant difference in spleen size between patients with and without analgesic abuse. On average, the spleens of the patients with analgesic nephropathy were smaller than those of normal population. Conclusions. The spleen was not enlarged in our patients and splenomegaly was not a part of analgesic syndrome in our patients with analgesic nephropathy treated with haemodialysis.
Summary		Izhodišča. Analgetična nefropatija je eksogena tubulointersticijska bolezen ledvic s progresivnim kliničnim potekom in pogosto z nastankom papilarne nekroze. Opisana je tudi splenomegalija kot del analgetičnega sindroma. Namen raziskave je bil, da ugotovimo velikost vranice pri bolnikih z analgetično nefropatijo, zdravljenih s kronično hemodializo, in jo primerjamo z velikostjo pri bolnikih kontrolne skupine. Metode. Z ultrazvočnim pregledom smo izmerili največjo površino vranice v cm2 pri bolnikih z analgetično nefropatijo, zdravljenih s hemodializo. To smo primerjali s površino vranice pri kontrolni skupini (naključno izbrani bolniki, usklajeni glede starosti in spola, zdravljeni s kronično hemodializo, brez podatkov o zlorabi analgetikov). Rezultati. Nismo ugotovili statistično pomembne razlike v površini vranice med bolniki z analgetično nefropatijo, zdravljenimi s kronično hemodializo, in kontrolno skupino. Povprečna površina vranice je bila manjša tudi od povprečne površine vranice pri zdravi populaciji. Zaključki. Ugotovili smo, da vranica ni povečana pri naših bolnikih z analgetično nefropatijo in da splenomegalija ni del analgetičnega sindroma pri naših bolnikih, zdravljenih s kronično hemodializo.
Descriptors		KIDNEY FAILURE, CHRONIC HEMODIALYSIS SPLEEN KIDNEY DISEASES ANALGESICS