Author/Editor | Pirkmajer, Sergej; Chibalin, Alexander V. | |
Title | NO turns on Na,K-ATPase in skeletal muscle | |
Type | članek | |
Publication year | 2016 | |
ISSN | 1748-1716 - Acta physiologica (Oxford, England) | |
Language | eng | |
Abstract | Tight regulation of Na,K-ATPase activity in skeletal muscle is essential for muscle function and whole-body homeostasis. Activity of Na,K-ATPase adapts dynamically to acute alterations in demands for Na+ and K+ transport in skeletal muscle. This is particularly important during muscle contractions, when increased activity of Na,K-ATPase opposes contraction-induced displacement of Na+ and K+ across sarcolemma and thereby maintains muscle excitability and contractility (Clausen, 2003). | |
Keywords | skeletal muscle homeostasis muscle function skeletne mišice homeostaza delovanje mišic |