| Author/Editor | Lainščak, Mitja; Coats, Andrew J. | |
| Title | The PARADIGM of ARNI's: Assessing reasons for non-implementation in heart failure | |
| Type | članek | |
| Vol. and No. | Letnik 212, št. 1 June | |
| Publication year | 2016 | |
| Volume | str. 187-189 | |
| ISSN | 2352-9067 - International journal of cardiology | |
| Language | eng | |
| Abstract | Several trials have targeted neutral endopeptidase to demonstrate benefits for patients with heart failure. In the PARADIGM-HF trial, a combination of sacubitril and valsartan was superior to enalapril in reducing the risk of death and of hospitalization for heart failure. In this editorial we apply the trial to heart failure population at large to estimate what proportion of patients might actually be treated in daily practice. | |
| Descriptors | Heart failure Endopeptidases Srčno popuščanje Endopeptidaze Drug therapy Therapeutic use Uporaba za zdravljenje |