Author/Editor		Ružić-Sabljić, Eva; Cerar Kišek, Tjaša
Title		Borrelia genotyping in Lyme disease
Type		članek
Vol. and No.		Letnik 10, št. suppl. 1
Publication year		2016
Volume		str. 6-14
ISSN		1874-3722 - The open dermatology journal
Language		eng
Abstract		Borrelia burgdorferi sensu lato is the causative agent of Lyme borreliosis, multisystem disorder characterized by a wide spectrum of clinical manifestations. Different borrelia species can lead to distinct clinical presentations, but some species were associated with defined clinical manifestation like Borrelia afzelii with skin manifestations, Borrelia garinii with central nervous system disorders and Borrelia burgdorferi sensu stricto with Lyme arthritis. Ixodes ticks represent the main vectors of B. burgdorferi sensu lato; wild animals, lizards and birds are the natural reservoir of borrelia. Genotyping of borrelia strains is of great importance for epidemiological, clinical, and evolutionary studies. Numerous methods are available for the genotyping of B. burgdorferi sensu lato based either on whole genome or PCR based typing. Typing methods differ in their approach and target, many of them were implemented more or less successfully for diagnostic purposes.
Keywords		Borrelia burgdorferi Lyme borreliosis genotyping Borrelia burgdorferi lymska borelioza genotipizacija