Author/Editor | Obermajer, Nataša; Dahlke, Marc H. | |
Title | (Compl)Ex-Th17-Treg cell inter-relationship | |
Type | članek | |
Vol. and No. | Letnik 5, št. 1 | |
Publication year | 2016 | |
ISSN | 2162-4011 - Oncoimmunology | |
Language | eng | |
Abstract | Codependent development and Th17-to-FoxP3+ T cell inter-conversion account for the enigmatic coexistence of IL17-producing and FoxP3+ cells in tumor-associated inflammation. In addition to Treg cells, exTh17-FoxP3+ cells present a novel subpopulation of FoxP3+ cells. Yin-yang of IL17+ and FoxP3+ cells presents an important principle for improved approaches in cancer immunotherapy. | |
Keywords | T cell plasticity suppressor cells sterile inflammation plastičnost T celic supresorske celice sterilno vnetje |