Author/Editor     Obermajer, Nataša; Dahlke, Marc H.
Title     (Compl)Ex-Th17-Treg cell inter-relationship
Type     članek
Vol. and No.     Letnik 5, št. 1
Publication year     2016
ISSN     2162-4011 - Oncoimmunology
Language     eng
Abstract     Codependent development and Th17-to-FoxP3+ T cell inter-conversion account for the enigmatic coexistence of IL17-producing and FoxP3+ cells in tumor-associated inflammation. In addition to Treg cells, exTh17-FoxP3+ cells present a novel subpopulation of FoxP3+ cells. Yin-yang of IL17+ and FoxP3+ cells presents an important principle for improved approaches in cancer immunotherapy.
Keywords     T cell plasticity
suppressor cells
sterile inflammation
plastičnost T celic
supresorske celice
sterilno vnetje