| Author/Editor | Rajšp, Patric; Križmarić, Miljenko | |
| Title | Cardiovascular changes in simulation of spaceflight zero-gravity and Mars gravity | |
| Translated title | Kardiovaskularne spremembe pri simulaciji vesoljskih poletov ničelne gravitacije in gravitacije Marsa | |
| Type | članek | |
| Source | In: Zbornik predavanj Maribor : Fakulteta za zdravstvene vede | |
| Publication year | 2016 | |
| Volume | str. 247-249 | |
| Language | slv | |
| Abstract | Uvod Kardiovaskularni modeli simulirane umetne gravitacije vključujejo simulacijo gravitacije na Marsu (20⁰ glede na vodoravno lego), ničelno gravitacijo (-6⁰ od vodoravne lege, glava navzdol) in gravitacijo Zemlje (80⁰). Metode Izvedli smo kvantitativno študijo, ki je vključila 4 zdrave prostovoljce, ki smo jih postavili z glavo navzdol (-6⁰) in z dvignjeno glavo pri 20⁰ in 80⁰. Ocenjevali smo iztis srca (SV), minutni iztis srca (CO), krvni tlak (BP), frekvenco srca (HR) in sistemsko upornost ožilja (TPR). Rezultati Srednji arterijski tlak se je zmanjšal iz položaja 20⁰ (gravitacija Marsa) v položaj -6⁰ (ničelna gravitacija) iz 79%3 mmHg na 68%9 mmHg (p<0,001). TPR prav tako pade s 1140%171 dina s cm-5 na 639%168 dina s cm-5 (p<0,001). Diskusija in zaključek V primerjavi z dvigom glave (20⁰), se v simulaciji z glavo navzdol (-6⁰), pomaknejo tekočine iz abdomna v prsni koš in se poveča frekvenca srca, zmanjša pa BP in TPR.Introduction Cardiovascular models of simulated artificial gravity simulated Mars gravity (20⁰ from supine), zero gravity (- 6⁰ from supine, head down) and standing at Earth (80⁰). Methods We conducted quantitative study involving 4 healthy volunteers who were studied while head down (-6⁰) and head up tilt (HUT) at 20⁰ and 80⁰. Stroke volume (SV), cardiac output (CO), blood pressure (BP), heart rate (HR) and sistemic vascular resistivity (TPR) were evaluated. Results Mean arterial pressure was decreased from position 20⁰ (Mars gravity) to possition -6⁰ (zero gravity) from 79%3 mmHg to 68%9 mmHg (p<0.001). TPR was also decreased from 1140%171 dina s cm-5 to 639%168 dina s cm-5 (p<0.001). Discussion and conclusion Compared to head up tilt (20⁰), in head down (-6⁰) simulation, fluid shifts from the abdomen to the chest and increaese heart rate and decrease BP and TPR. | |
| Keywords | simulirana gravitacija gravitacija Marsa ničelna gravitacija hemodinamika simulated gravity Mars gravity zero gravity hemodynamics |