Author/Editor		Lučovnik, Miha; Tul, Nataša; Lozar Krivec, Jana; Kolenc, Urša; Jeverica, Samo
Title		Prevalenca kolonizacije z bakterijo Streptococcus agalactiae pri nosečnicah v Sloveniji, 2013-2014
Translated title		Prevalence of Streptococcus agalactiae colonisation among pregnant women in Slovenia, 2013-2014
Type		članek
Vol. and No.		Letnik 85, št. 7/8
Publication year		2016
Volume		str. 393-400
ISSN		1581-0224 - Zdravniški vestnik
Language		slv
Abstract		Background: Streptococcus agalactiae is the leading cause of preventable invasive neonatal infections. Detection of maternal colonisation and use of antimicrobial prophylaxis during labour is a standard preventative approach. Very few data about the prevalence of colonisation with S. agalactiae among pregnant women in Slovenia are available. Methods: We performed a retrospective study of consecutive samples from pregnant women screened for S. agalactiae colonisation with enrichment culture during the period 2013-2014. Basic demographic data, specimen type, timing and result of the assay were analysed. Cumulative antimicrobial susceptibility for the positive samples was calculated. Results: During 2 years study period 1564 pregnant women were tested. Mean age 31 years (18-46 years). Among samples received, majority were vaginal swabs 57,0 % (n=893). Recommended combined vaginal-rectal swabs were received in 12,9 % (n=192). Overall prevalence of maternal colonisation was 17,1 % (n=268) and did not differ with regard to specimen type. Resistance or reduced susceptibility to erythromycin and clindamycin was 23,1 % (n=62) and 20,9 % (n=56), respectively. No resistance to penicillin and vancomycin was detected. Conclusions: Few pregnant women get screened for S. agalactiae in Slovenia. Nevertheless, high colonisation rate was detected on a large sample size. Most samples were taken during the proposed period between 35-37 week of pregnancy. Recommended combined vaginal-rectal were less frequently taken for screening than vaginal swabs only. Penicillin and vancomycin remains universally active against S. agalactiae. However, erythromycin and clindamycin resistance was high.
Keywords		pregnancy neonatal infections Streptococcus agalactiae nosečnost neonatalne okužbe Streptococcus agalactiae