Author/Editor     Premuš Marušič, Alenka; Locatelli, Igor; Mrhar, Aleš; Caprnda, Martin; Gaspar, Ludovit; Adamek, Mariusz; Kruzliak, Peter; Petrovič, Danijel
Title     Influence of prescribed blood products on the incidence of deep vein thrombosis and pulmonary embolism in surgical patients
Type     članek
Publication year     2017
Volume     str. str.
ISSN     1076-0296 - Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Language     eng
Abstract     Deep vein thrombosis (DVT) and pulmonary embolisms (PEs) are common complications after surgical procedures. The influence of prescribed blood products on the occurrence of DVT and PE was evaluated in postsurgical patients in this retrospective case-control study. The records of 286 surgical patients were analyzed: DVT (n = 52), PE (n = 92), and a control group (n = 142). The amounts of prescribed blood, blood products, and vitamin K were reviewed, together with appropriate prescribing of low-molecular-weight heparins. The influence of prescribed blood products on the occurrence of DVT or PE was analyzed using multinomial logistic regression. We demonstrated a significant difference between the test and control groups (P < .05) in relation to receiving packed red blood cells. Treatment with red blood cells was associated with an increased risk of PE but not DVT. Patients who developed PE after surgery were hospitalized for longer (median 10 days) than patients with DVT (median 6 days). There was no difference between the test and control groups concerning treatment with fresh frozen plasma. Inadequate thromboprophylaxis significantly increased the likelihood of DVT. There is a connection between receiving packed red blood cells and occurrence of postoperative PE in surgical patients. Thus, patients receiving red blood cells should be monitored more closely after surgery, as they are more likely to develop PE postoperatively.
Keywords     prevention of venous thromboembolism
red blood cells
vitamin K
preprečevanje venske trombembolije
rdeče krvne celice