Author/Editor     Banjac, Igor; Petrovic, Marija; Akay, Mehmet H.; Janowiak, Lisa M.; Radovancevic, Rajko; Nathan, Sriram; Patel, Manish; Loyalka, Pranav; Kar, Biswajit; Gregorič, Igor
Title     Extracorporeal membrane oxygenation as a procedural rescue strategy for transcatheter aortic valve replacement cardiac complications
Type     članek
Vol. and No.     Letnik 62, št. 1
Publication year     2016
Volume     str. 1-4
ISSN     1058-2916 - ASAIO journal (American Society for Artificial Internal Organs : 1992)
Language     eng
Abstract     Cardiovascular complications during or after transcatheter aortic valve replacement (TAVR) are associated with extremely high mortality, but extracorporeal membrane oxygenation (ECMO) can be used as procedural rescue option to improve outcomes when patients experience respiratory or cardiac arrest. From 2012 to 2014, 230 patients underwent TAVR and 10 patients (4.3%) required emergent venous-arterial ECMO support. Mean age was 83 years, median Society of Thoracic Surgeons (STS) score was 15, and mean aortic gradient was 45 mm Hg. Median left ventricular ejection fraction was 35%. Access for most ECMOs was femoral; two patients required central arterial and femoral venous access. Extracorporeal membrane oxygenation was initiated in response to hemodynamic collapse due to perforation of left ventricle (n = 2), aortic root rupture (n = 1), moderate-to-severe aortic insufficiency (n = 1), left main impingement (n = 1), valve embolization (n = 1), severe hypotension and cardiac arrest after prolonged rapid pacing sequence (n = 1), ventricular fibrillation (n = 2), and ventricular tachycardia (n = 1). Median time of ECMO support was 87 minutes. There were three hospital deaths. Post-TAVR mean aortic gradient was 8 mm Hg and median hospital stay was 19 days. Additional procedures included valve-in-valve placement (n = 1), percutaneous coronary intervention (n = 1), surgical LV repair (n = 2), surgical valve replacement (n = 1), aortic root rupture repair, and coronary bypass grafting (n = 1). Extracorporeal membrane oxygenation is rescue therapy for hemodynamic instable patients who develop TAVRrelated cardiac complications.
Keywords     extracorporeal membrane oxygenation
transcatheter aortic valve replacement
hemodynamic collapse
zunajtelesna membranska oksigenacija
transkateterska aortna nadomestna zaklopka
hemodinamski kolaps