Author/Editor | Schaerer, K | |
Title | Proteinuria | |
Type | članek | |
Source | Slov Pediatr | |
Vol. and No. | Letnik 2, št. 1-3 | |
Publication year | 1995 | |
Volume | str. 130-3 | |
Language | eng | |
Abstract | Increased protein excretion in urine (proteinuria) is recognized to be of diagnostic value for differentiation of various renal disorders. It was found to be an important predictor for evaluating the progression of nephropathies, as in some forms of glomerulonephritis or in diabetic nephropathy. Proteinuria in these disorders may be reduced and thereby progression delayed by the use of angiotensin converting enzyme inhibitors. Traditionally, one may distinguish between prerenal, renal and postrenal forms of proteinuria. This paper reviews the pathophysiology of renal handling of diferent proteins excreted in urine, current standard methods used for measurements, and the diagnostic value of glomerular and tubular proteinuria in children with renal and metabolic disorders. 4 mg total proteinuria per square m per hour are taken as the upper normal limit. In addition, a short outline is given for evaluating children with asymptomatic proteinuria. The importance of 12-hour over-night urine collections is stressed. | |
Descriptors | PROTEINURIA CHILD |