Author/Editor		Niaudet, P
Title		Schoenlein-Henoch purpura nephritis
Type		članek
Source		Slov Pediatr
Vol. and No.		Letnik 2, št. 1-3
Publication year		1995
Volume		str. 138-42
Language		eng
Abstract		Glomerular disease occurs in approximately 30 pct of patients with Schoenlein-Henoch purpura. Hematuria is the most common symptom often associated with the variable amounts of proteinuria. The nephrotic syndrome is common in severe forms. Nephritis is characterized by the presence of mesangial deposits which contain IgA. By light microscopy, the glomerular involvement is that of a mesangiopathy with varying degrees of hypercellularity and crescent formation. Patients with proteinuria lower than 1 g per day at presentation have an excellent long term prognosis and only those with marked proteinuria are at risk of developing chronic renal failure. The proportion of crescents on initial biopsy is the most important prognostic guide although remarkable recovery is possible. Patients with severe forms of the disease (nephrotic syndrome, crescentic glomerulonephritis) should be treated as early as possible and methylprednisolone pulses seem to be efficient in these cases.
Descriptors		NEPHRITIS PURPURA, SCHOENLEIN-HENOCH HEMATURIA GLOMERULONEPHRITIS, IGA CHILD