Author/Editor		Gugić Kevo, Jasenka; Zadravec-Zaletel, Lorna; Oblak, Irena
Title		Treatment-related cardiovascular toxicity in long-term survivors of testicular cancer
Type		članek
Vol. and No.		Letnik 51, št. 2
Publication year		2017
Volume		str. 221-227
ISSN		1318-2099 - Radiology and oncology
Language		eng
Abstract		Testicular cancer is the most common malignancy in young men. Considering increasing incidence, exceptionally high cure rate, as well as long life expectancy, assessment of long term toxicity in testicular cancer survivors is of great importance. In the last decades a major effort has been made in order to reduce toxicity of treatment, while maintaining its high effectiveness. Conclusions Actual knowledge on treatment toxicity is based on outdated treatment modalities. Hopefully, modern treatment modalities could reduce toxicity, but, there is no firm confirmation for that at the moment, as data dealing with late sequelae of modern treatment of testicular cancer are not available yet due to the short period of observation. The life-threatening cardiovascular toxicity in testicular cancer survivors is major complication of platinum-based chemotherapy, mediastinal radiotherapy and even subdiaphragmatic radiotherapy.
Keywords		rak mod srčno-žilni sistem toksičnost pozne posledice testicular cancer cardiovascular toxicity long-term survivors