Author/Editor		Stacey, Andrew; Lavrič, Alenka; Thaung, Caroline; Siddiq, Samreen; Sagoo, Mandeep
Title		Solitary iris plasmacytoma with anterior chamber crystalline deposits
Type		članek
Vol. and No.		Letnik 36, št. 7
Publication year		2017
Volume		str. 875-877
ISSN		0277-3740 - Cornea
Language		eng
Abstract		Purpose: To report a case of solitary iris plasmacytoma success- fully treated with ruthenium plaque radiotherapy. Methods: A 44-year-old white woman presented with pain in the right eye and raised intraocular pressure. Her medical history included breast cancer treated 11 years earlier with lumpectomy, lymph node clearance, chemotherapy, and radiotherapy. On exam- ination, the right iris had a tan-colored mass with crystalline deposits visible on the mass surface and on the corneal endothelium. The fundus and left eye were normal. An anterior segment ultrasound scan showed a mass with mixed internal echogenicity and internal blood fl ow. Results: An iris biopsy showed an in fi ltrate of plasma cells. Immunohistochemistry for kappa and lambda light chains dem- onstrated lambda light chain res triction. Systemic hematologic investigations including compl ete blood count, serum parapro- teins, bone marrow biopsy, and full-body magnetic resonance image were normal. The monoclonal plasma cell in fi ltrate was consistent with a solitary iris plasmacytoma. The mass was treated with ruthenium plaque radiotherapy. After 4 years of follow-up, the mass remained regressed, and no systemic myeloma has developed. Conclusions: Iris plasmacytoma is rare and should prompt systemic evaluation to rule out multiple myeloma. Solitary iris plasmacytoma can be successfully treated with plaque radiotherapy.
Keywords		multiple myeloma cornea ruthenium plaque radiotherapy