Author/Editor		Cilenšek, Ines; Mankoč Ramuš, Sara; Globočnik Petrovič, Mojca; Petrovič, Danijel
Title		The glutathione reductase (GSR) polymorphisms (rs1002149 and rs8191009) and diabetic retinopathy in Slovenian subjects with type 2 diabetes mellitus
Type		članek
Vol. and No.		Letnik 1, št. 5
Publication year		2016
Volume		str. 1-5
Language		eng
Abstract		The present work was carried out to evaluate a possible association between two polymorphisms (rs1002149 and rs8191009) in the GSR gene coding for antioxidant enzyme, and DR in 804 unrelated Slovene subjects (Caucasians) with T2DM. No differences were observed in genotype distribution between the two groups for either polymorphism in the GSR gene. No significant differences in serum 8-OHdG levels among subjects with DR stratified according to three possible genotypes were observed. In our study, we did not demonstrate an association between either rs1002149 or rs8191009 and DR in subjects with T2DM.
Keywords		diabetes type 2 diabetic retinopathy oxidative stress diabetes tip 2 diabetična retinopatija oksidativni stres