Author/Editor     Štuhec, Matej
Title     Trimethoprim-sulfamethoxazole-related hallucinations
Type     članek
Vol. and No.     Letnik 36, št. 2
Publication year     2014
Volume     str. 230.e7-230.e8
ISSN     0163-8343 - General hospital psychiatry
Language     eng
Abstract     Although adverse drug reactions are a well-recognized cause of mental status changes in the elderly, antimicrobials are not often implicated. Trimethoprim-sulfamethoxazole-induced hallucinations in immune-competent patient with switching to nitrofurantoin and risperidone, without associated polypharmacy, have not been reported in the literature. In this case report, we present an 86-year-old Caucasian immune-competent female with major depressive disorder and insomnia who developed hallucinations when treated with two trimethoprim-sulfamethoxazole tablets (80 mg/400 mg) in every 12 hours (4 tablets daily) because of lower urinary infection. After trimethoprim-sulfamethoxazole discontinuation and switching to nitrofurantoin and risperidone, symptoms significantly improved.
Keywords     psihiatrični neželeni učinki
nitrofurantoin
geriatrično poročilo
trimetoprim sulfametoksazol