Author/Editor		Thunnissen, Erik; Allen, Timothy Craig; Adam, Julien; Aisner, Dara L.; Beasley, Mary Beth; Borczuk, Alain C.; Cagle, Philip T.; Capelozzi, Vera Luiza; Cooper, Wendy
Title		Immunohistochemistry of pulmonary biomarkers
Type		članek
Vol. and No.		Letnik no. , št. Vol.
Publication year		2017
Volume		str. str.
ISSN		0003-9985 - Archives of pathology & laboratory medicine
Language		eng
Abstract		The use of immunohistochemistry for the determination of pulmonary carcinoma biomarkers is a well-established and powerful technique. Immunohistochemisty is readily available in pathology laboratories, is relatively easy to perform and assess, can provide clinically meaningful results very quickly, and is relatively inexpensive. Pulmonary predictive biomarkers provide results essential for timely and accurate therapeutic decision making; for patients with metastatic non-small cell lung cancer, predictive immunohistochemistry includes ALK, (ROS1, EGFR in Europe), and programmed death ligand-1 (PD-L1) testing. Handling along proper methodologic lines is needed to ensure patients receive the most accurate and representative test outcomes.
Keywords		pljučni biomarkerji imunohistokemija patologija pulmonary biomarkers immunohistochemistry pathology