Author/Editor     Horvat, Nejc; Locatelli, Igor; Kos, Mitja; Janežič, Ana
Title     Medication adherence and health-related quality of life among patients with chronic obstructive pulmonary disease
Type     članek
Vol. and No.     Letnik 68, št. 1
Publication year     2018
Volume     str. 117-125
ISSN     1330-0075 - Acta pharmaceutica (Zagreb, Croatia)
Language     eng
Abstract     This study evaluated medication adherence and health-related quality of life (HRQoL) of Slovenian patients with chronic obstructive pulmonary disease (COPD) and examined the factors associated with HRQoL. Demographic and therapy information was collected from 65 patients through interviews. The St. George's Respiratory Questionnaire and the Morisky Medication Adherence Scale were used to evaluate HRQoL and adherence, resp. A multiple linear regression model was used to assess the association between the factors and HRQoL. The mean St. George's Respiratory Questionnaire score (range 0-100, with higher scores indicating lower HRQoL) was 41.4. COPD affected patients daily activities more than their social and psychological functioning. Slightly more than 53 % of the patients were optimally adherent, while 12 % were non-adherent. Patients with lower HRQoL had a larger number of medications for concomitant diseases, experienced COPD exacerbation in the last year, and had less education. No statistically significant correlation was found between medication adherence and HRQoL.
Descriptors     Kronična obstruktivna pljučna bolezen
Keywords     chronic obstructive pulmonary disease
healthrelated quality of life