Author/Editor     Veller-Fornasa, C; Fadel, A; Peruzzo, S; Peserico, A
Title     Pyoderma gangrenosum associated with IgA paraproteinemia: treatment with cyclosporin A and prednisone
Type     članek
Source     Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.     Letnik 4, št. 1
Publication year     1995
Volume     str. 27-30
Language     eng
Abstract     A 58-year-old woman with a 20-year history of recalcitrant pyoderma gangrenosum asssociated with IgA paraproteinemia was treated with cyclosporin A 5 mg/kg/day combined with prednisone 30 mg/day without significant amelioration. After raising the dose of cyclosporin A to 10 mg/kg a rapid improvement was observed. Subsequently the cyclosporin A and prednisone doses were reduced progressively and a complete cure was achieved after 7 months of treatment. Three years later no relapse has occurred on a maintenance therapy consisting of 3 mg/kg/day of cyclosporin A and 6 mg/day of prednisone.
Descriptors     PYODERMA GANGRENOSUM
CYCLOSPORINE
PREDNISONE
PARAPROTEINEMIAS
IGA