Author/Editor | Veller-Fornasa, C; Fadel, A; Peruzzo, S; Peserico, A | |
Title | Pyoderma gangrenosum associated with IgA paraproteinemia: treatment with cyclosporin A and prednisone | |
Type | članek | |
Source | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. and No. | Letnik 4, št. 1 | |
Publication year | 1995 | |
Volume | str. 27-30 | |
Language | eng | |
Abstract | A 58-year-old woman with a 20-year history of recalcitrant pyoderma gangrenosum asssociated with IgA paraproteinemia was treated with cyclosporin A 5 mg/kg/day combined with prednisone 30 mg/day without significant amelioration. After raising the dose of cyclosporin A to 10 mg/kg a rapid improvement was observed. Subsequently the cyclosporin A and prednisone doses were reduced progressively and a complete cure was achieved after 7 months of treatment. Three years later no relapse has occurred on a maintenance therapy consisting of 3 mg/kg/day of cyclosporin A and 6 mg/day of prednisone. | |
Descriptors | PYODERMA GANGRENOSUM CYCLOSPORINE PREDNISONE PARAPROTEINEMIAS IGA |