Author/Editor		Verkhratsky, Alexei; Zorec, Robert
Title		Astroglial signalling in health and disease
Type		članek
Vol. and No.		, št. Vol.
Publication year		2018
Volume		str. str.
ISSN		0304-3940 - Neuroscience letters
Language		eng
Abstract		Astrocytes, the neural homeostatic cells, play a key role in the information processing in the central nervous system. They express multiple receptors which respond to a number of chemical messengers and get excited as evidenced by an increase in second messengers in short and delayed time domains. Astrocytes secrete numerous neuroactive agents and mount various homeostatic responses. These signal integrating functions are key factors of neuropathology (better termed astroneuropathology): they provide for neuroprotection through both homeostatic support and astroglial reactivity; failure in astroglial defensive or supporting capabilities facilitates evolution of neurological disorders.
Keywords		astrocytes synaptic transmission calcium astrociti sinaptični prenos kalcij