Author/Editor		Schäfer, Valentin S.; Chrysidis, Stavros; Dejaco, Christian; Duftner, Christina; Iagnocco, Annamaria; Bruyn, George A. W .; Carrara, Greta; D'Agostino, Maria-Antonietta; Hočevar, Alojzija
Title		Assessing vasculitis in giant cell arteritis by ultrasound
Type		članek
Publication year		2018
Volume		str. str.
ISSN		0315-162X - The Journal of rheumatology
Language		eng
Abstract		Objective To test the reliability of Outcome Measures in Rheumatology Clinical Trials (OMERACT) consensus-based ultrasound definitions for normal and vasculitic temporal and axillary arteries in patients with giant cell arteritis (GCA) and in controls. Methods A preliminary 1-day meeting and a full 3-day meeting fulfilling OMERACT Ultrasound Group guidelines were held. Temporal and axillary arteries were examined at 2 timepoints by 12 sonographers on 4 patients with GCA and 2 controls. The aim was to test inter- and intrareader reliability for normal findings, halo sign, and compression sign. In both meetings, patients had established GCA. Pathology was more recent in the full meeting, which was preceded by 6 h of training. Scanning time was 15-20 min instead of 10-13 min. Results In the preliminary exercise, interreader reliabilities were fair to moderate for the overall diagnosis of GCA (Light [keta] 0.29-0.51), and poor to fair for identifying vasculitis in the respective anatomical segments (Light [keta] 0.02-0.46). Intrareader reliabilities were moderate (Cohen [keta] 0.32-0.64). In the main exercise, interreader reliability was good to excellent (Light [keta] 0.76-0.86) for the overall diagnosis of GCA, and moderate to good (Light [keta] 0.46-0.71) for identifying vasculitis in the respective anatomical segments. Intrareader reliability was excellent for diagnosis of GCA (Cohen [keta] 0.91) and good (Cohen [keta] 0.71-0.80) for the anatomical segments. Conclusion OMERACT-derived definitions of halo and compression signs of temporal and axillary arteries are reliable in recent-onset GCA if experienced sonographers (> 300 examinations) have 15-20 min for a standardized examination with prior training and apply > 15 MHz probes.
Keywords		giant cell arteritis assessing vasculitis ultrasound velikanski celični arteritis ocenjevanje vaskulitisa ultrazvok