Author/Editor     Strnad, Matej; Lešnik, Damjan; Križmarić, Miljenko
Title     Arterial blood gas changes during cardiac arrest and cardiopulmonary resuscitation combined with passive oxygenation/ventilation
Type     članek
Vol. and No.     Letnik 46, št. 11
Publication year     2018
Volume     str. 4605-4616
ISSN     1473-2300 - The Journal of international medical research
Language     eng
Abstract     Objective High-fidelity simulators can simulate physiological responses to medical interventions. The dynamics of the partial arterial pressure of oxygen (PaO2), partial arterial pressure of carbon dioxide (PaCO2), and oxygen pulse saturation (SpO2) during simulated cardiopulmonary resuscitation (CPR) were observed and compared with the results from the literature. Methods Three periods of cardiac arrest were simulated using the METI Human Patient Simulator (Medical Education Technologies, Inc., Sarasota, FL, USA): cardiac arrest, chest compression-only CPR, and chest compression-only CPR with continuous flow insufflation of oxygen (CFIO). Results In the first period, the observed values remained constant. In the second period, PaCO2 started to rise and peaked at 63.5mmHg. In the CFIO period, PaCO2 slightly fell. PaO2 and SpO2 declined only in the second period, reaching their lowest values of 44mmHg and 70%, respectively. In the CFIO period, PaO2 began to rise and peaked at 614mmHg. SpO2 exceeded 94% after 2 minutes of CFIO. Conclusions The METI Human Patient Simulator accurately simulated the dynamics of changes in PaCO2. Use of this METI oxygenation model has some limitations because the simulated levels of PaO2 and SpO2 during cardiac arrest correlate poorly with the results from published studies.
Descriptors     Cardiopulmonary Resuscitation
Heart Arrest
Kardiopulmonalno oživljanje
Srčni zastoj
Keywords     patient-specific modeling
blood gas analysis
high-fidelity simulator
pulmonary ventilation