Author/Editor     Campbell, Matthew D.; Babić, Dražen; Bolčina, Uroš; Smirčić-Duvnjak, Lea; Tankova, Tsvetalina; Mitrakou, Asimina; Kempler, Peter; Janež, Andrej
Title     High level of clinical inertia in insulin initiation in type 2 diabetes across Central and South-Eastern Europe
Type     članek
Publication year     2019
Volume     str. str.
ISSN     0940-5429 - Acta diabetologica
Language     eng
Abstract     Aims Little is known regarding initiation of insulin therapy in type 2 diabetes (T2D) in Central and South-Eastern Euro- pean countries. Therefore, we conducted a survey to characterise the prescribing practices of specialist diabetes healthcare professionals in this region and assessed factors that influence clinical decision-making regarding insulin initiation in T2D. Methods A cross-sectional survey sampled 211 specialist diabetes healthcare prescribers from five Central and South- Eastern European countries (Bulgaria, Croatia, Greece, Hungary, and Slovenia). A structured questionnaire was developed which surveyed current clinical practices and influencing factors, barriers to insulin initiation, and combination therapy prescribing preferences. Result Only 9.4% (20 of out of 211 respondents) of healthcare professionals would initiate insulin therapy in T2D patients at the recommended HbA1c threshold of 7-7.9% [53-63 mmol/mol]. Large regional differences were evident in insulin initiation thresholds (>-9.0% [>-75 mmol/mol]: Bulgaria 80.8% vs. Slovenia 13.3%). Psychological distress was recorded as the major barrier to insulin initiation. Health insurance regulations were ranked more important than personal clinical experience and clinical guidelines in clinical decision-making. Information from peers was more influential than manufacturer information, clinical experience, and continuous medical education, respectively, for insulin initiation. Conclusions Despite large regional variation, there is widespread delay of insulin initiation from specialist diabetes healthcare professionals in Central and South-Eastern Europe.
Keywords     insulin therapy initiation
type 2 diabetes mellitus
clinical inertia
začetek zdravljenja z insulinom
sladkorna bolezen tip 2
klinična inercija