Author/Editor		Rozman, Janez; Ribarič, Samo
Title		A setup for selective infrared stimulation of an isolated porcine vagus nerve
Type		članek
Vol. and No.		, št. Vol. 292
Publication year		2019
Volume		str. 97-104
ISSN		0924-4247 - Sensors and actuators. A, Physical
Language		eng
Abstract		We developed an experimental setup for selective infrared (IR) stimulation of an isolated porcine vagus nerve. The system consists of an infrared IR diode (IR diode), providing an optical power of 6.5 W at [lambda] = 1937 nm, high-quality fibre optic multimode patch cables, an optical pulse shaper, and a custom made experimental chamber. The system allows researchers to vary: the radiant exposure from 0 to 2.3 Jcm-2, vertical displacement of the IR aperture, nominal pulse duration that could be set at 250, 500, and 800 [micro]s, and frequency of IR pulses between 15 and 50 Hz, enabling the assessment of the relationship between different patterns of IR pulses and the elicited nerve response (NR). The main contribution resulting from the study is an optical pulse shaper, which generates IR pulses with a rise-time of approximately 100 ns, and facilitatesan appropriate coupling efficiency via a Grin Lens Fibre Coupler/Fibre Optic Positioner. Another novelty is the 3D positioning device of the experimental chamber, which enables the ex-vivo assessment of spatial and fibre-type selectivity.
Keywords		kratkovalovna infrardeča svetloba stimulacija živcev živec Vagus short-wave infrared light nerve stimulation Vagus nerve