Author/Editor		Andersen, BB; Korbo, L
Title		Purkinje cell number and size, comparison of human and rat cerebella
Type		članek
Source		Acta Stereol
Vol. and No.		Letnik 12, št. 2
Publication year		1993
Volume		str. 295-8
Language		eng
Abstract		Estimates of total number and mean volume of Purkinje cells in five human and nine rat cerebella were obtained using stereological methods based on unbiased principles and estimators. The average total number of Purkinje cells was 30.5 10/6 (CV = SD/mean = 0.13) ub gznabs abd 0.61 10/6 (CV = 0.21) in rats. Thus the total number of Purkinje cells was 50 times higher in the human compared with rats, while numerical density per mm/3 was 13 times lower in humans (0.81 10/3) compared with rats (10.1 10/3). The nucleator was applied to estimate the number weighted mean volume of the large and unevenly distributed Purkinje cells. In humans the mean volume of Purkinje cell perikaryon is 14,250 micro m/3 (CV = 23%). The data are compared with the mean Purkinje cell erikaryon volume in rats, 5,300 micro m/3, with a CV of 5%. Expectedly, the variation in Purkinje perikaryon volume between individuals are larger in humans than the individual variation between rats.
Descriptors		CEREBELLUM PURKINJE CELLS RATS HISTOLOGICAL TECHNIQUES CELL SIZE CELL COUNT