Author/Editor     Savic, Louise C.; Khan, David A.; Kopač, Peter; Clarke, Russel C.; Cooke, Peter J.; Dewachter, Pascale; Ebo, Didier G.; Garcez, Tomaz; Garvey, Lene Heise; Guttormsen, Anne Berit
Title     Management of a surgical patient with a label of penicillin allergy
Type     članek
Vol. and No.     Letnik 123, št. 1
Publication year     2019
Volume     str. e82-e94
ISSN     1471-6771 - British journal of anaesthesia
Language     eng
Abstract     Unsubstantiated penicillin-allergy labels are common in surgical patients, and can lead to significant harm through avoidance of best first-line prophylaxis of surgical site infections and increased infection with resistant bacterial strains. Up to 98% of penicillin-allergy labels are incorrect when tested. Because of the scarcity of trained allergists in all healthcare systems, only a minority of surgical patients have the opportunity to undergo testing and de-labelling before surgery. Testing pathways can be modified and shortened in selected patients. A variety of healthcare professionals can, with appropriate training and in collaboration with allergists, provide testing for selected patients. We review how patients might be assessed, the appropriate testing strategies that can be used, and the minimum standards of safe testing.
Descriptors     Allergy and immunology
Drug hypersensitivity
Penicillins
Antibiotic prophylaxis
Surgery
Surgical procedures, operative
Bacterial infections
Surgical wound infection
Alergija in imunologija
Preobčutljivost za zdravila
Penicilini
Antibiotična profilaksa
Kirurgija
Operativni kirurški postopki
Bakterijske okužbe
Okužbe kirurških ran
Keywords     provokacijsko testiranje za zdravila
operacije
drug provocation testing
surgical procedures