Author/Editor | Kovačič, B; Vlaisavljević, V | |
Title | Influence of pentoxifylline on hyperactivity of human sperm | |
Type | članek | |
Source | In: Aburumieh A, Bernat E, Dohr G, et al editors. 9th world congress on in vitro fertilization and assisted reproduction; 1995 Apr 3-7; Vienna. Bologna: Monduzzi Editore, | |
Publication year | 1995 | |
Volume | str. 573-5 | |
Language | eng | |
Abstract | Pentoxifylline (PF) affects the motility of human sperm, which is perceptible by multiexposure photography (MEP). In normozoospermic samples (n=23), the tracks of sperm treated with PF (n=449) were shorter (12.8+-3.4) as compared to the control group (n=459) (13.6+-3.7) (p less th. 0.0005), probably owing to larger movement "microamplitudes" and the sperm changed their direction of movement several times (2.9+-1.8 vs. 2.3 +-1.7) (p less th. 0.0001), which are the characteristics of hyperactivity. PF did cause an increase in concentration of motile sperm in washed oligozoospermic samples (n=23) (4.9+-4.2 vs. 3.5+-3.9) ( less th. 0.001). | |
Descriptors | PENTOXIFYLLINE SPERM MOTILITY PHOTOGRAPHY SPERM COUNT |