| Author/Editor | Gašljević, Gorana; Hertl, Kristijana; Gazić, Barbara; Lamovec, Janez; Žgajnar, Janez | |
| Title | Reducing indications for radial scar surgical excision in Slovenian breast cancer screening program | |
| Type | članek | |
| Vol. and No. | , št. Vol. 45 | |
| Publication year | 2020 | |
| Volume | str. [1-4] | |
| ISSN | 1532-8198 - Annals of diagnostic pathology | |
| Language | eng | |
| Abstract | Purpose:Management of the radial scar (RS)/complex sclerosing lesion (CSL) diagnosed by core needle biopsy(CNB) in breast cancer screening population (BCSP) is controversial due to its intrinsic malignant potential. Weaimed to determine (i) the rate of upgrade of the RS/CSL to malignant lesions and (ii) radiological characteristicsand CNB histopathologicalfindings of the lesions related to the upgrade of the RS/CSL to malignant lesions aftersurgical excision in our BCSP.Patients and methods:Database of Slovenian National Breast Cancer Screening Program was checked for termsRS/CSL in all patients who underwent CNB in the period 2008%2018. The ratios of upgrade from CNB RS/SCL tomalignant lesions after surgical excision were calculated with specific interest to the radiological characteristicsand the CNB patohistologicallyfindings of the lesions.Results:Of 162 patients with diagnosis of RS/CSL on the CNB, 121/156 (78%) cases underwent surgical exci-sion. 6 of 121 (5%) cases were upgraded to a malignant diagnosis in surgical specimen, 3 cases of invasivecarcinoma and 3 cases of DCIS, respectively. Five of the upgraded cases (5/6, 83.3%) showed atypical epithelialproliferative lesions (AEPL) on CNB. In one upgraded case without AEPL the lesion presented as 33 mm archi-tectural distortion with microcalcifications on the mammogram.Conclusions:In BCSP setting RS/CSL without AEPL/papilloma and those measuring less than 2 cm in the largestdiameter can be followed radiologically. Increasing the number of cores and adequate sampling of the peripheryand the centre of the RS/CSL improves the pick-up rate of associated atypia/malignancy | |
| Keywords | rak dojke radialni rez mamografija kirurgija breast cancer radial scar mammography screening surgery |