Author/Editor		Bosak, Kristina; Coha, Sandra; Jelavić, Silvana; Grošić, Vladimir; Bajić, Žarko; Polašek, Ozren; Ćelić Ružić, Mirela; Filipčić, Igor; Švab, Vesna
Title		Time from the admission as the predictor of aggressive behavior of inpatients with schizophrenia spectrum disorder
Type		članek
Publication year		2020
Volume		str. str.
ISSN		0033-2720 - The Psychiatric quarterly
Language		eng
Abstract		The aim was to assess the incidence of aggressive events (AE) committed bypatients diagnosed with schizophrenia spectrum disorethder (SSD) after the first 7 days of hospitalization in psychiatric institution, in comparison to other psychiatric patients. This retrospective cohort study was performed at Psychiatric Hospital "Sveti Ivan", Zagreb, Croatia, using hospital safety records of all patients admitted between 2015 and 2017. Primary outcome was the proportion of patients who committed AE more than a week after the admission to the hospital. Secondaryoutcome was the time in days from admission to the first incident of AE. The primary analysis was performed using a multivariable binary logistic regression.SSD patients committed AE more often than other patients (incidence rate ratio 3.97(95% CI 2.35-6.69;p< 0.001; FDR q = 0.002), but these occurred earlier in thecourse of hospitalization: median (IQR) 2 (1-10) days from admission compared to11 (2-32) days in other patients. SSD patients had significantly and clinically relevantly lower odds for AE after the first week of hospitalization adjusted forthe large number of pre-planned possible confounders (OR = 0.10; 95% CI 0.02-0.45;p= 0.003; FDR q = 0.002). SSD patients seem to express more aggression earlier in the course of hospitalization. Findings of this study indicate that hospitalization-inherent AE risk factors may play an important role in the etiologyof AE and inpatients aggressive behavior. Their possible moderating effect shouldbe included in risk-assessment instruments.
Keywords		accidents aggression hospitalization nesreče agresija hospitalizacija