Author/Editor		Jagrič, Tomaž
Title		Complications in gastric cancer surgery
Type		članek
Vol. and No.		Letnik 2, št. 1
Publication year		2020
Volume		str. 13-22
ISSN		2591-2275
Language		eng
Abstract		Backgrounds. Knowledge of complications is of paramount importance when treating gastric cancer patients. We deter-mined the factors that predisposed morbidity and mortality.Methods. We analyzed the results of 1,211 patients with gastric cancer operated on with curative intent.Results. Cumulative perioperative morbidity in the 27-year period was 22.5%. Cumulative perioperative mortality in the 27-year period was 4%. Age (HR 1.017; 95% CI 1.003%1.032; p = 0.019) and tumor grade (HR 1.002; 95% CI 1.001%1.004; p = 0.008) were significantly associated with perioperative morbidity. Perioperative mortality was significantly associat-ed with perioperative chemoradiotherapy (HR 0.183; 95% CI 0.042%0.797; p = 0.024), American Society of Anesthesiolo-gists score (HR 1.873; 95% CI 1.076%3.261; p = 0.026), and the period of operation. Perioperative mortality decreased from 8.6% in the first 3-year period to 0% in the last 3-year period. The mortality rate fell below 4% after 6 years or 361 patients operated on.Conclusion. Our analysis showed that apart from factors that indicate the general state of the patient only the experience of a center has an impact on perioperative morbidity and mortality. Centralization of patients in a high-volume center can there-fore be the only means of ensuring the best results for gastric cancer patients and excellent long-term survival.
Keywords		gastric cancer morbidity mortality rak želodca obolevnost umrljivost