Author/Editor		Omersel, Jasna; Šmid, Alenka; Zore, Taja; Slavec, Lara; Avsec, Damjan; Prodan Žitnik, Irena; Osredkar, Joško; Božič, Borut; Marc, Janja
Title		Laboratorijska diagnostika covid-19
Translated title		Laboratory diagnosis of covid-19
Type		članek
Vol. and No.		Letnik 71, št. 2
Publication year		2020
Volume		str. 112-120
ISSN		0014-8229 - Farmacevtski vestnik : strokovno glasilo slovenske farmacije
Language		slv
Abstract		V spopadanju s pandemijo bolezni covid-19 so bile neprimerljivo uspešnejše države z obsežnim laboratorijskim testiranjem, doslednim spremljanjem in izolacijo okuženih oseb. K hitrejši in učinkoviti zdravniški obravnavi pomembno doprinese laboratorijska diagnostika. Njena vloga je, da izbira najboljše metode, ki so v danem trenutku na razpolago in zagotavljajo kakovostne, zanesljive rezultate v najkrajšem možnem času. V članku predstavljamo spoznanja o imunskem odzivu po okužbi s SARS-CoV-2, pristope v diagnostiki virusnih okužb in značilnosti dobre diagnostične metode. Predstavljena je diagnostika covid-19 z vidika prepoznavanja aktivne (virusna RNA) in prebolele okužbe (protitelesa proti virusnim antigenom) kot tudi spremembe v biokemijskih parametrih in uporabnost diagnostičnih rezultatov za uspešno obvladovanje pandemije SARSCoV-2.In the fight against covid -19, countries where extensive laboratory testing, consistent monitoring and isolation of infected individuals were implemented have been incomparably more successful. Laboratory diagnostics contributes to faster and more efficient medical decisions. Its role is to select the best methods available at a given time, and to provide high quality and reliable results in the shortest possible time. Herein, we present the latest findings on the immune response to a SARS-CoV-2 infection, approaches in the diagnosis of viral infections and the characteristics of a good diagnostic method. We present the diagnostics of covid-19 from recognising active (viral RNA) and past infection (antibodies against viral antigens) to changes in biochemical parameters and the applicability of diagnostic results for successful management of the SARS-CoV-2 pandemic.
Descriptors		Zakonodaja Imunski odziv
Keywords		diagnostika SARS-CoV-2 molekularne metode serološki testi