Author/Editor		Niespodziana, Katarzyna; Borochova, Kristina; Pazderova, Petra; Schlederer, Thomas; Astafyeva, Natalia; Baranovskaya, Tatiana; Barbouche, Mohamed-Ridha; Beltiukov, Evgenyi; Berger, Angelika; Borzova, Elena; Bousquet, Jean; Zidarn, Mihaela; Valenta, Rudolf
Title		Towards personalization of asthma treatment according to trigger factors
Type		članek
Vol. and No.		Letnik 145, št. 6
Publication year		2020
Volume		str. 1529-1534
ISSN		1097-6825 - The Journal of allergy and clinical immunology
Language		eng
Abstract		Asthma is a severe and chronic disabling disease affecting more than 300 million people world-wide. While in the past few drugs for treatment of asthma were available, new treatment options are currently emerging which appear to be highly effective in certain subgroups of patients. Accordingly there is a need for biomarkers which allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on micro-arrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed which may discriminate two of the most common forms of asthma, i.e., allergen- and virus-triggered asthma. In this perspective we argue that classification of asthma patients according to these common trigger factors may open new possibilities for personalized management of asthma.
Descriptors		Allergy and immunology Asthma Signs and symptoms, respiratory Rhinovirus Allergens Microarray analysis Precision medicine Alergija in imunologija Astma Respiratorni znaki in simptomi Rinovirus Alergeni Analiza mikromrež Personalizirana medicina Diagnosis Therapy Diagnosis Therapy Diagnostika Terapija Diagnostika Terapija
Keywords		wheeze sopenje