Author/Editor		Plankar Srovin, Tina; Avramoska, Tanja; Bahovec, Natalija; Bizjak, Simona; Granda, Aida; Lah, Liza Lea; Mrvič, Tatjana; Osterman, Veronika; Prunk, Petra; Rožič, Mojca; Šivic, Urška; Vincek, Katarina; Zakotnik, Breda
Title		Koronavirusna bolezen (COVID-19) pri otrocih
Translated title		Coronavirus disease (COVID-19) in children
Type		članek
Vol. and No.		Letnik 27, št. 3
Publication year		2020
Volume		str. 107-117
ISSN		1318-4423 - Slovenska pediatrija [Združenje pediatrov Slovenije]
Language		slv
Abstract		Coronaviruses generally cause a mild respiratory tract infection. In the last two decades, three types of coronavirus have spread from animal reservoirs to humans causing severe diseases with a high mortality rate. The outbreak of new coronavirus disease - COVID-19, which is caused by SARS-CoV-2, began in China and spread worldwide in less than 3 months.Main routes of viral transmission are via droplets and contact with soiled surfaces and fomites. The incubation period is estimated to be 4-6 days.Most children have mild disease with nonspecific symptoms and signs of upper respiratory tract infection, in a smaller proportion, gastrointestinal symptoms are present. The most common encountered symptoms are fever and cough. The disease course is mostly self-limiting with uneventful recovery in 1-2 weeks. Severe disease is rare (up to 6 %). From late April we are witnessing emerging reports of children with a severe inflammatory disease resembling Kawasaki disease and toxic shock syndrome. Pathogenesis of this syndrome is not yet well understood; the severe inflammatory response might be caused by activation of the immune system by superantigen induced by the virus.Currently, there is no specific treatment for COVID-19. A few vaccines are in the pipeline, which might help not only in controlling and limiting the current epidemic but eventually preventing similar epidemics in the future.
Keywords		COVID-1 otroci pandemija COVID-1 children pandemic