Author/Editor		Čerk, M; Kregar, T; Škrbec, M; Kadivec, M; Pečarič-Meglič, N
Title		Neuroimaging of multiple sclerosis
Type		članek
Source		In: Vodušek DB, editor. Proceedings of the Symposium on multiple sclerosis with the 11th dr. Janez Faganel memorial lecture; 1995 Oct 6-7; Ljubljana. Ljubljana: University institute of clinical neurophysiology,
Publication year		1995
Volume		str. 42-6
Language		eng
Abstract		The diagnosis of multiple sclerosis depends ultimately on the clinical history and physical findings. However, neuroimaging techniques can add to detection of multiple lesions disseminated in time and in space and so to earlier diagnosis of multiple sclerosis. MRI is the most accurate paraclinical test in multiple sclerosis and has now replaced CT in the assessment of multiple sclerosis. MRI has been associated with a high level of sensitivity and a lower level of specifity. MRI can be used for both the diagnosis of multiple sclerosis and for monitoring treatment effects. As a diagnostic tool, cerebral MRI is a very sensitive technique revealing multifocal white matter abnormalities in 95-98% of patients with clinical definite multiple sclerosis. However, specificity is a major problem and many posible diagnoses may be made from the appearance of white matter lesions in the brain. Since 1993 we examined 386 patients with clinically suspected multiple sclerosis. The diagnosis was confirmed in 169 patients (44%). The diagnosis of multiple sclerosis was suspected by MRI in 197 patients, who were referred to MRI with diagnoses others than multiple sclerosis.
Descriptors		MULTIPLE SCLEROSIS NEURORADIOGRAPHY