Author/Editor		Bartenjev, Mark S.; Isaković-Vidović, Suzana; Bartenjev, Igor
Title		Topical imiquimod for management of recurrent lentigo maligna melanoma in situ
Type		članek
Vol. and No.		Letnik 28, št. 1
Publication year		2020
Volume		str. 34-37
ISSN		1330-027X - Acta dermatovenerologica Croatica : ADC
Language		eng
Abstract		Topical imiquimod is a medication approved for the treatment of external genital and perianal warts, actinic keratosis, and superficial basal cell carcinoma. There have also been reports of its successful use in patients with lentigo maligna melanoma in situ. An 80-year-old female patient was diagnosed with lentigo maligna melanoma in situ which was then surgically removed. After several recurrences, nonsurgical treatment using topical 5% imiquimod was introduced. At 9-month follow-up the skin was completely healed with no evidence of cancer recurrence. In select cases, topical imiqui-mod seems to be an effective alternative to surgical treatment of melanoma in situ (MIS). Further studies are necessary to assess the successfulness of this treatment method.
Keywords		lentigo melanom imikvimod nekirurška terapija lentigo melanoma imiquimod nonsurgical therapy