Author/Editor		Bošnjak, Matic; Kojc, Nika
Title		Reparative perineural hyperplasia in the gastric wall
Type		članek
Publication year		2021
Volume		str. str.
ISSN		1066-8969 - International journal of surgical pathology
Language		eng
Abstract		Reparative perineural hyperplasia is an incidental and probably under reported reactive histologic finding thus far only reported in the setting of healing wounds or adjacent to a dermatofibroma in cutaneous specimens. It is characterized by a focal concentric proliferation of cytologically bland spindled perineurial cells and is hence considered a benign histologic mimic of neoplastic perineural invasion. Thus, it may present a diagnostic pitfall and we the refore consider it asa valuable entity to be aware of. To the best ofour knowledge, this brief case report is the first toconveythatrep-arative perineural hyperplasia may also occur in the gastrointestinal tract. It may therefore be a ubiquitous reactive histological phenomenon relating to previous surgical or traumatic wounds in various sites, that is, outside the thusfar established setting of skin reexcision specimens.
Keywords		perineural invasion reparative perineural hyperplasia immunohistochemistry perinevralna invazija reparativna perinevralna hiperplazija imunohistokemija