Author/Editor		Večerić-Haler, Željka; Kojc, Nika; Sever, Matjaž; Zver, Samo; Švajger, Urban; Poženel, Primož; Pretnar-Hartman, Katrina; Urdih, Tereza; Mlinšek, Gregor; Oblak, Manca; Aleš, Andreja; Ihan, Alojz; Buturović-Ponikvar, Jadranka; Halloran, Philip F.; Arnol, Miha
Title		Capillary leak syndrome with kidney transplant failure following autologous mesenchymal stem cell therapy
Type		članek
Vol. and No.		, št. Vol. 8
Publication year		2021
Volume		str. 1-7
ISSN		2296-858X - Frontiers in Medicine (Online)
Language		eng
Abstract		Mesenchymal stem cells (MSCs) have attracted great interest in the field of kidney transplantation due to their immunomodulatory and reparative properties. In registered clinical trials, MSCs have been used before, at the time of, or early after transplantation and have been reported to be well-tolerated with no serious safety concerns. No results are available on the use of MSCs in the late post-transplant period. Here, we present a case report of a severe systemic complication mimicking capillary leak syndrome with ultimate kidney transplant failure after autologous transplantation of MSCs used as rescue treatment of late antibody-mediated kidney allograft rejection.
Keywords		mesenchymal stem cell kidney transplant kidney graft failure mezenhimske izvorne celice presaditev ledvice odpoved ledvičnega presadka