Author/Editor		Žiberna, Lovro; Jenko Pražnikar, Zala; Petelin, Ana
Title		Serum bilirubin levels in overweight and obese individuals
Type		članek
Vol. and No.		Letnik 10, št. 8
Publication year		2021
Volume		str. 1-16
ISSN		2076-3921
Language		eng
Abstract		Obesity is a chronic condition involving low-grade inflammation and increased oxidative stress; thus, obese and overweight people have lower values of serum bilirubin. Essentially, bilirubin is a potent endogenous antioxidant molecule with anti-inflammatory, immunomodulatory, antithrombotic, and endocrine properties. This review paper presents the interplay betweeen obesity-related pathological processes and bilirubin, with a focus on adipose tissue and adipokines. We discuss potential strategies to mildly increase serum bilirubin levels in obese patients as an adjunctive therapeutic approach.
Keywords		adipokini antioksidanti proti-vnetje bilirubin debelost prekomerna telesna masa adipokines antioxidant anti-inflammatory bilirubin obesity overweight