Author/Editor		Boštjančič, Emanuela; Večerić-Haler, Željka; Kojc, Nika
Title		The role of immune-related miRNAs in the pathology of kidney transplantation
Type		članek
Vol. and No.		Letnik 11, št. 8
Publication year		2021
Volume		str. 1-15
ISSN		2218-273X - Biomolecules
Language		eng
Abstract		MicroRNAs (miRNAs) are members of the non-coding regulatory RNA family that play pivotal roles in physiological and pathological conditions, including immune response. They are particularly interesting as promising therapeutic targets, prognostic and diagnostic markers due to their easy detection in body fluids and stability. There is accumulating evidence that different miRNAs provide disease-specific signatures in liquid samples of distinct kidney injuries. Using experimental models and human samples, there have been numerous suggestions that immunerelated miRNAs are also important contributors to the development of different kidney diseases as well as important markers for monitoring response after kidney transplantation. However, there are limited data for understanding their function in the molecular pathways of allograft pathologies. In our review, we focused on microRNAs that are related to different aspects of immune response after kidney transplantation.
Keywords		mikroRNA (miRNA) presaditev ledvic imunski odziv microRNA (miRNA) kidney transplantation immune response