| Author/Editor | Komadina, R | |
| Title | Stereološke značilnosti zlomov proksimalne stegnenice (primerjava ročne, polavtomatske in avtomatske metode) | |
| Translated title | Histomorphometric characteristics of cancellous bone in fractures of the proximal femur (comparison of manual, semi-automatic and automatic method) | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Medicinska fakulteta | |
| Publication year | 1995 | |
| Volume | str. 83 | |
| Language | slo | |
| Abstract | Background. The commonest types of fractures of the proximal femur are the fractures of the neck and the trochanteric region. Their importance is rising extremely because of a higher percentage of elderly people in the developed countries of Europe and America. We analysed histomorphometrically bone samples taken during the operative procedure at the trochanteric region. We tried to prove the differences in bone quantity and bone quality in two different heights of proximal femoral fractures. According to 6-10 year older patients with the trochanteric fractures we expected greater osteoporosis in this group. Methods. Because of sex hormones influence we chose female population, aged from 65 to 80. The first group included 11 patients with femoral neck fractures while the second group included 8 patients with trochanteric fractures. Samples of bone taken at autopsy of 10 female patients died of myocardial infarction or cerebrovascular insult represented the control group. The study was prospective. We performed manual, semi-automatic and automatic histomorphometric analysis and proved their validity, reliability, accuracy and efficiency. Results. Structural variables and static variables of bone turnover are presented in tables and graphs. The patients with the femoral neck fractures had greater areal density and specific areal density of bony trabeculae than the controls (p less than 0.05). The patients with trochanteric fractures had greater volume density and areal density of osteoid portion in trabeculae than the controls (p less than 0.01). Other statistically significant differences were not proven. Validity of the manual method was 0.94, validity of the semi-automatic method was 0.91, validity of the automatic method was 0.67. Reliability of the semi-automatic method according to manual method as refference was 0.85, of the automatic method 0.99. Relative standard error presented accuracy.(trunc.) | |
| Descriptors | FEMORAL FRACTURES OSTEOPOROSIS BONE DENSITY AGED AUTOPSY HISTOLOGICAL TECHNIQUES |