Author/Editor     Skaza-Maligoj, A
Title     Razširjenost uretritisov pri moških v celjski regiji, ki jih povzroča Chlamydia trachomatis
Type     monografija
Place     Celje
Publisher     Medicinska fakulteta
Publication year     1995
Volume     str. 51
Language     slo
Abstract     Aim of the study. In our research project we studied the prevalence of Chlamydia trachomatic (CT) in men in the Region of Celje. We tested 44 men with urethral discharge (study group) and 218 healthy men (control group). Our objective were as fallows: - to know the frequency of urethritis caused by CT in men between 18 and 45 years of age; - to provide general practioners with the latests achievements on the field of laboratory diagnosis, treatment and complications after untreated chlamydial infections; - to carry out and evaluate three tests with two type of samples (urethral swabs and first void urine specimens) which were used for laboratory diagnosis. We valuated all tests in both samples. Study group. In the study group CT antigenes were detected by the direct immunofluorescence test (EIA), DIF test and the DNA hybridization test in urine specimens. Control group. In the control group CT antigenes were detected by the DIF test, EIA test and the DNA hybridization test in urine sediments. Results in study group. The prevalence of chlamydial urethritis in the study group, detected by the DIF test in urethral swabs, was 11.4 percent (5/44). The overall prevalence of CT in this group (detected with the combination of all three tests) was 15.5 percent (7/44). Results in control group. The prevalence of asymptomatic chlamydial urethritis in the control group, detected in urine sediments by the DNA hybridization test, was 2.8 percent (6/218). The overall prevalence of CT in this group, detected with the combination of the DNA hybridazation and EIA test, was 3.2 percent (7/218 ). Treatment. Patients with chlamydial urethritis and their sex partners were treated with a single 1 g dose of azithromycin. The results of our research project were shown to the general practioners of the area and was also stressed the importance of raising awareness among patients which would restrict the spreading of sexually transmitted diseases (STDs). Conclusion.(trunc.)
Descriptors     URETHRITIS
CHLAMYDIA TRACHOMATIS
FLUORESCENT ANTIBODY TECHNIQUE, DIRECT
IMMUNOENZYME TECHNIQUES
NUCLEIC ACID HYBRIDIZATION