Author/Editor		Vander Poorten, Vincent; Meulemans, Jeroen; Beitler, Jonathan J.; Piazza, Cesare; Kowalski, Luiz P.; Mäkitie, Antti A.; Paleri, Vinidh; Rinaldo, Alessandra; Thomas Robbins, K.; Strojan, Primož
Title		Salvage surgery for residual or recurrent laryngeal squamous cell carcinoma after (chemo)radiotherapy
Type		članek
Vol. and No.		Letnik 47, št. 11
Publication year		2021
Volume		str. 2711-2721
ISSN		0748-7983 - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Language		eng
Abstract		Nonsurgical primary treatment of early and advanced laryngeal squamous cell carcinoma, employing radiotherapy with or without chemotherapy, is considered a standard of care in many centers throughout the world. When patients have persistent or recurrent disease after non-surgical treatment, salvage surgery is frequently the only remaining potentially curative treatment. Depending on the extent of the residual/recurrent disease, different surgical salvage options are at the surgeon's disposal. In selected cases with limited local disease, salvage transoral laser microsurgery, transoral robotic surgery and open partial laryngectomies can be employed to achieve cure while preserving laryngeal function. For more advanced cases total laryngectomy is necessary. Identifying situations with unacceptable results from surgical salvage may guide future therapies.
Keywords		ohranjajoča kirurgija rak grla onkološki izidi napovedni dejavniki conservation surgery laryngeal carcinoma oncological outcomes prognostic factors