Author/Editor		Ng, Wai Tong; Tsang, Raymond K. Y.; Beitler, Jonathan J.; De Bree, Remco; Coca-Pelaz, Andrés; Eisbruch, Avraham; Mäkitie, Antti A.; Mendenhall, William M.; Nuyts, Sandra; Strojan, Primož
Title		Contemporary management of the neck in nasopharyngeal carcinoma
Type		članek
Vol. and No.		Letnik 43, št. 6
Publication year		2021
Volume		str. 1949-1963
ISSN		1043-3074 - Head and neck
Language		eng
Abstract		Up to 85% of the patients with nasopharyngeal carcinoma present with regional nodal metastasis. Although excellent nodal control is achieved with radiotherapy, a thorough understanding of the current TNM staging criteria and pattern of nodal spread is essential to optimize target delineation and minimize unnecessary irradiation to adjacent normal tissue. Selective nodal irradiation with sparing of the lower neck and submandibular region according to individual nodal risk is now emerging as the preferred treatment option. There has also been continual refinement in staging classification by incorporating relevant adverse nodal features. As for the uncommon occurrence of recurrent nodal metastasis after radiotherapy, surgery remains the standard of care.
Keywords		rak glave in vratu ploščatocelični rak obsevanje radioterapija head and neck cancer squamous cell cancer radiotherapy radiotherapy treatment