Author/Editor | Dragoš, V; Podrumac, B; Kralj, B; Bartenjev, I; Dolenc, M | |
Title | Terbinafine in tinea capitis due to Microsporum canis | |
Type | članek | |
Source | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. and No. | Letnik 4, št. 4 | |
Publication year | 1995 | |
Volume | str. 195-7 | |
Language | eng | |
Abstract | Ten children within the age range of 3-9 years with non-inflammatory tinea capitis due to Microsporum canis were evaluated in an open clinical test. The pilot study ran from January to November 1994. Each child was given oral terbinafine (Lamisil) for 6 weeks once daily according to body weight (dose range 62,5-125 mg/day). The therapy was continued with topical 1 percent terbinafine cream for another 6 weeks. After 6 weeks of oral terbinafine application all mycological investigations remained positive, whereas cultures turned out to be negative in 5 cases (50 percent). After 12 weeks the KOH and Wood tests became negative in 6 (60 percent), culture was negative in 6 (60 percent). No systemic or topical side effects were noted, so we found terbinafine safe and well tolerated. Further studies with longer oral terbinafine treatment in tinea capitis due to Microsporum canis are suggested. | |
Descriptors | TINEA CAPITIS CHILD MICROSPORUM |