| Author/Editor | Kmetec, A | |
| Title | Nekateri metabolni dejavniki pomembni pri urolitiazi | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Medicinska fakulteta | |
| Publication year | 1995 | |
| Volume | str. 48 | |
| Language | slo | |
| Abstract | In the first part of work metabolic analyses of first morning urine samples were determined at 204 patients included by randomisation from all slovenian regions. Exclusion criteria were cystine, urate lithiasis, hyperparahyroidism and phosphate lithiasis. Analyses were done for pH, amount of citrate, urate oxalate and calcium in urine. The presence of metabolic disturbances was determined in 62,3 percent. One disturbance was evaluated in 51,5 percent, twice in 10,8 percent. Anomaly most frequently statet was lowered citrates in 78 percent, next high oxalate in 15,2 percent and high calcium in urine in only 6,7 percent. Among combined metsbolic disturbances lowered citrate and high oxalate predominate in 68,2 percent. No difference was evaluated between pH determination in group with urinary metabolic disturbances and group without. From this group 32 patients were folowed proved by documentation; 16 of them with urine metabolic distubance and 16 without during a period of 3 to 24 month after a stone treatment. Frequency and percent of stone relapses were higher in the group with disturbances during period 3 to 12 month. Afer 12 months some patient were lost of control further consluclusions were hazardous. In second part of this work, study was designed to investigate the effect of mineral solution Dolit-Mg in 27 patients with proven calcium oxalate lithiasis and urine metabolic disturbances by evaluation blood serum parameters and 24-hours urine collections. All patients were included in protocol by informed consent, visits were in outpatients department. Dolit-Mg solution consumation was 500ml divided fuor times daily during two weeks. Blood speciments were taken before and after two weeks, solution drinking, 24-hour urine collection was done before, on 13. day and on last day solution drinking.(trunc.) | |
| Descriptors | URINARY CALCULI URINE MINERAL WATERS LITHOTRIPSY CALCIUM HYPEROXALURIA CITRATES |