Author/Editor		Pink, Anna; Przybelski, Scott A.; Krell-Roesch, Janina; Stokin, Gorazd Bernard; Roberts, Rosebud O.; Mielke, Michelle M.; Spangehl, Kathleen A.; Knopman, David S.; Jack, Clifford R.; Petersen, Ronald C.; Geda, Yonas Endale
Title		Cortical thickness and anxiety symptoms among cognitively normal elderly persons
Type		članek
Vol. and No.		Letnik 29, št. 1
Publication year		2017
Volume		str. 60-66
ISSN		0895-0172 - The Journal of neuropsychiatry and clinical neurosciences
Language		eng
Abstract		The authors conducted a cross-sectional study to investigate the association between anxiety symptoms and cortical thickness, as well as amygdalar volume. A total of 1,505 cognitively normal participants, aged s70 years, were recruited from the Mayo Clinic Study of Aging in Olmsted County, Minnesota, on whom Beck Anxiety Inventory and 3T brain MRI data were available. Even though the effect sizes were small in this community-dwelling group of participants, anxiety symptoms were associated with reduced global cortical thickness and reduced thickness within the frontal and temporal cortex. However, after additionally adjusting for comorbid depressive symptoms, only the association between anxiety symptoms and reduced insular thickness remained significant.
Keywords		anxiety symptoms elderly persons neuropsychology simptomi anksioznosti starejše osebe nevropsihologija