Author/Editor		Hancock, John M.; Chaleeprom, Witcha; Chaleeprom, Worawan; Dale, James; Gibbs, Adrian J.
Title		Replication slippage in the evolution of potyviruses
Type		članek
Vol. and No.		Letnik 76, št. 12
Publication year		1995
Volume		str. 3229-3232
ISSN		0022-1317 - Journal of General Virology
Language		eng
Abstract		Recently published evidence for sequence repetition in potyvirus genomes prompted us to analyse the published complete genome sequences and coat protein gene sequences of viruses of this family for evidence of replication slippage. Five of nine complete genomic sequences and 17 of 32 coat protein genes had significant sequence repetitions. Most of these were in coat protein genes, although the 5' region of the turnip mosaic virus genome also showed evidence of slippage. The results suggest that replication slippage may be involved in the evolution of viruses, as well as prokaryotes and eukaryotes, and that slippage can occur in both RNA and DNA when it is being replicated.
Keywords		viruses evolution genomic sequences virusi evolucija sekvence genoma