Author/Editor		Hancock, John M.; Gates, Hilary
Title		The informatics of high-throughput mouse phenotyping
Type		članek
Source		In: Mouse as a model organism : from animals to cells Dordrecht New York : Springer
Publication year		2011
Volume		str. 77-88
Language		eng
Abstract		Now that not only the mouse genome sequence but also the ability to carry out high throughput manipulation of mouse ES cells is in place, projects are underway to understand the functions of individual mouse genes in a systematic manner. Central to this will be the systematic analysis of the phenotypes of mutant mouse lines. EUMODIC, the first large-scale project to screen mouse knockout lines for disease-related phenotypes is underway and experience shows the neces- sity of a well-organised bioinformatics infrastructure for the capture, analysis and dissemination of the data emerging from such projects. Here we discuss the funda- mental requirements for such a bioinformatics infrastructure, progress so far and the developments that will be required in future.
Keywords		EUMODIC fenotipizacija miši infrastruktura bioinformatike EUMODIC mouse phenotyping bioinformatics infrastructure